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Bacteria Defeats Last Effective Antibiotic

Bacteria Defeats Last Effective Antibiotic

Alex Wierbinski's picture

By Alex Wierbinski - Posted on 14 June 2019



Salmonella Resistant to Antibiotics of Last Resort Found in US.
North Carolina State University, June 13, 2019.

MCR-3.1 in US
"...found a gene that gives Salmonella resistance to antibiotics of last resort in a sample taken from a human patient in the U.S. The find is the first evidence that the gene mcr-3.1 has made its way into the U.S. from Asia."

Full Antibiotic Resistance
"The drug resistance gene in question - known as mcr-3.1 - gives Salmonella resistance to colistin, the drug of last resort for treating infections caused by multidrug-resistant Salmonella."


Original Article

Visual of the Last Gasp of The Age of Antibiotics

The mcr-9 gene's protein structure graphic, by Ahmed Gaballa, Cornell University.

The mcr-9 jumping gene's protein structure graphic depicts the differing protein chains (solid color ribbons) and the protein surface (mesh) surrounding it, by Ahmed Gaballa, Cornell University. Large Image.


Bacteria Defeats Last Effective Antibiotic

New 'Jumping' Superbug Gene Discovered, Resistant to Last-Resort Antibiotic,
Cornell University, May 6, 2019.


"Doctors deploy the antibiotic colistin when all other infection-fighting options are exhausted. But resistance to colistin has emerged around the globe, threatening its efficacy."

"Mcr-9 is the latest in this new series of "mobilized colistin-resistance" genes - originally discovered in 2015."

Jumping Gene
"...food scientists discovered mcr-9, a new stealthy, jumping gene so diabolical and robust that it resists," colistin, which is, "...one of the world's few last-resort antibiotics."

"...found mcr-9 in the genome of a strain of foodborne pathogen salmonella."

Plasmid Sharing
"The gene is moveable. It jumps."
Plasmid Sharing Spreading Bacteria Resistance Defeating Antibiotics

Last Bacterial Defense Broken
Spreadable Resistance, And Spreading to Other Bacteria Now
"In treatments, if colistin does not work, it literally could mean death for patients. If colistin resistance spreads, a lot of people will die."


Bottom Line

New Age Dawning
Humanity stands at the end of the Age of Antibiotics. We are here not only because of the deftness of bacteria, though their brilliance at manipulating life contributes. Nor do we face this crisis due to any failure of the antibiotics themselves. We face the end of antibiotic effectiveness only because of how we have mis-used antibiotics.

Misuse It, Lose It
The emerging lesson from antibiotics is already quite clear: We lose the things we misuse. Antibiotics are merely one area in which our abuses of technology are not just, "remodeling," our own character, but are simultaneously changing Nature's biological responses to us, while dramatically increasing Nature's physical, "operating temperatures."
These multi-dimensional changes to us and our environment are completely remodeling the, "interface," being the relationships not just between, "Man & Nature," but changing the relationship between all living things with each other, while at the same time all of Nature is attempting to cope with our radically changing this planet's physical environment and climate.

Watch & Learn
We are watching the operating principal of, "misuse it, loose it," operating across every aspect of the human interface with each other and Nature.

The most fundamental lesson here is that uncontrolled hunger eventually eats itself.




Subsequent Superbug Research

Nov 2019
New Superbug Camouflage



About Antimicrobial Resistance
Centers for Disease Control & Prevention

"Each year in the U.S., at least 2 million people are infected with antibiotic-resistant bacteria, and at least 23,000 people die as a result."



The Real Resistance
Recent Research

Two Works of Research: Bacteria Moving Effectively to Counter Human Antibiotics


Don’t Cut Yourself: Your Risks of Deadly, Antibiotic-Resistant Infections are Rising


Plasmid Sharing Parties
Spreading Bacterial Resistance Defeating Antibiotics


Superbug Patrol
Watching the Bacteria Carefully, & The Bottom Line: A New World of Germs




May 2019 News of Man & Nature








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health news, fitness news, antibiotic resistance, antibiotic resistant, bacteria, mcr-9, gene, colistin, colistin resistance, mobile, plasmid sharing, salmonella


Originally Published
2019-05-07 12:46:22

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